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Development of TaqMan probes targeting the four major celiac disease epitopes found in α-gliadin sequences of spelt (Triticum aestivum ssp. spelta) and bread wheat (Triticum aestivum ssp. aestivum).

Benjamin DjoudalbayePierre BertinYordan MuhovskiEmmanuelle EscarnotDominique Mingeot
Published in: Plant methods (2017)
The results obtained in this study provide useful tools to study the immunogenic potential of expressed α-gliadin sequences from Triticeae accessions such as spelt and bread wheat. The application of the designed probes to contrasted spelt accessions revealed a high variability and interesting low canonical epitope expression levels in the Asian spelt accessions studied.
Keyphrases
  • celiac disease
  • small molecule
  • poor prognosis
  • single cell
  • single molecule
  • cancer therapy
  • binding protein
  • drug delivery
  • human health
  • transcription factor
  • long non coding rna