The Impact of Androgen Receptor and Histone Deacetylase 1 Expression on the Prognosis of Ductal Carcinoma In Situ.

Choong Man Lee Il-Young Chung Yangsoon Park Keong Won Yun Hwi Gyeong Jo Hye Jin Park Hee Jin Lee Sae Byul Lee Hee Jeong Kim Beom Seok Ko Jong Won Lee Byung Ho Son Sei-Hyun Ahn Namshin Kim

Published in: Journal of breast cancer (2020)

Comparative gene expression analysis of pure DCIS revealed 8 DEGs among recurring cases. External validation with IHC suggested that the absence of AR and overexpression of HDAC1 are associated with a greater risk of long-term invasive REC of pure DCIS.

Keyphrases

histone deacetylase
gene expression
poor prognosis
dna methylation
cell proliferation
single cell
transcription factor
binding protein
long non coding rna