Safety and efficacy of direct oral anticoagulants in comparison to warfarin in obese patients with atrial fibrillation: A systematic review and meta-analysis.

Alla AdelkhanovaPrakash Raj OliDhan Bahadur ShresthaJurgen ShtembariVivek JhaGhanshyam ShanthaGeorge Michael BodziockMonodeep BiswasMuhammad Omer ZamanNimesh K Patel

Published in: Health science reports (2024)

Based on the findings from this meta-analysis, DOACs demonstrate superior safety and efficacy in obese patients with AF compared with VKAs. These results may have significant implications for guiding anticoagulation strategies in this patient population.

Keyphrases

direct oral anticoagulants
atrial fibrillation
venous thromboembolism
systematic review
adipose tissue
weight loss
metabolic syndrome
type diabetes
obese patients
oral anticoagulants
meta analyses
case report
bariatric surgery
case control
randomized controlled trial