Differences in social brain function in autism spectrum disorder are linked to the serotonin transporter: A randomised placebo-controlled single-dose crossover trial.
Nichol M L WongOttavia DipasqualeFederico TurkheimerJames L FindonRobert H WichersMihail DimitrovClodagh M MurphyVladimira StoenchevaDene M RobertsonDeclan G MurphyEileen DalyGrainne M McAlonanPublished in: Journal of psychopharmacology (Oxford, England) (2022)
Our findings suggest that the SERT-enriched functional network is dynamically different in ASD during processing of socially relevant stimuli. Whether this acute neurobiological response to citalopram in ASD translates to a clinical target will be an important next step.
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