Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers.

Haoyang Mi Shamilene Sivagnanam Courtney B Betts Shannon M Liudahl Elizabeth D Thompson Lisa M Coussens Aleksander S Popel

Published in: Cancer research (2022)

Quantitative image analysis of PDAC specimens reveals intertumoral and intratumoral heterogeneity of immune populations and identifies spatial immune architectures that are significantly associated with disease prognosis.

Keyphrases

single cell
high resolution
genome wide
gene expression
dna methylation
mass spectrometry