FDG-PET/CT activity leads to the diagnosis of unsuspected TB: a retrospective study.
Carolina GeadasCarlos Acuna-VillaordunaGustavo MercierMary B KleinmanC Robert HorsburghJerrold J EllnerKaren R JacobsonPublished in: BMC research notes (2018)
Patient records were searched using the words "positron emission tomography/computed tomography" and 24 codes for TB between 2004 and 2013. Patients with a diagnosis of TB and a PET/CT scan were included. Clinical and radiographic data were retrieved. PET/CT images were reviewed by an experienced radiologist. FDG-PET/CT scans revealed elevated FDG-uptake in lungs of five patients subsequently diagnosed with active (n = 3) or clinically inactive (n = 2) tuberculosis. Uptake magnitude was unrelated to disease activity. These findings suggest that tuberculosis latency may include periods of percolating inflammation of uncertain relationship to future disease risk.
Keyphrases
- pet ct
- positron emission tomography
- computed tomography
- mycobacterium tuberculosis
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- end stage renal disease
- pet imaging
- pulmonary tuberculosis
- magnetic resonance imaging
- ejection fraction
- newly diagnosed
- rheumatoid arthritis patients
- chronic kidney disease
- hiv aids
- deep learning
- contrast enhanced
- juvenile idiopathic arthritis
- peritoneal dialysis
- emergency department
- dual energy
- case report
- single cell
- convolutional neural network
- patient reported outcomes
- magnetic resonance
- electronic health record
- human immunodeficiency virus
- cord blood
- artificial intelligence
- hiv infected