Human adipose and synovial-derived MSCs synergistically attenuate osteoarthritis by promoting chondrocyte autophagy through FoxO1 signaling.

Jianqun WuSongqiang HuangYangyi YuQiang LianYang LiuWenfeng DaiQisong LiuYonghao PanGui-Ang LiuKai LiChao LiuGuangheng Li

Published in: Stem cell research & therapy (2024)

A combination of human ADSCs and SDSCs demonstrated higher potential than a single type of stem cell, demonstrating potential as a novel treatment for OA.

Keyphrases

endothelial cells
stem cells
signaling pathway
mesenchymal stem cells
pluripotent stem cells
cell death
rheumatoid arthritis
oxidative stress
type diabetes
human health
insulin resistance
metabolic syndrome
climate change
risk assessment
skeletal muscle