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Optimised infliximab monotherapy is as effective as optimised combination therapy, but is associated with higher drug consumption in inflammatory bowel disease.

David DrobneTina KurentSaša GolobPolona ŠveglPolona RajarJurij HanželMatic KoželjGregor NovakNataša SmrekarIvan FerkoljBorut Štabuc
Published in: Alimentary pharmacology & therapeutics (2019)
In this study, optimised infliximab monotherapy was as clinically effective as combination therapy but was associated with significantly higher infliximab consumption. The infliximab-sparing effect disappeared after azathioprine withdrawal.
Keyphrases
  • combination therapy
  • ulcerative colitis
  • emergency department
  • randomized controlled trial
  • robot assisted