Circulating tumour cells in patients with lung cancer universally indicate poor prognosis.

Fukang JinLei ZhuJingbo ShaoMina YakoubLukas SchmittChristoph ReißfelderSonja LogesAxel Benner Sebastian Schölch

Published in: European respiratory review : an official journal of the European Respiratory Society (2022)

CTCs indicate poor prognosis in patients with primary lung cancer, with CTCs in SCLC having a more pronounced prognostic effect. The prognostic value of CTCs detected by different markers varies; most evidence is available for the strong negative prognostic effect of epithelial CTCs.

Keyphrases

poor prognosis
circulating tumor cells
long non coding rna
induced apoptosis
endoplasmic reticulum stress