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Emergent canine visceral leishmaniasis in Argentina: Comparative diagnostics and relevance to proliferation of human disease.

Kyoko FujisawaCharlotte Silcott-NilesPoppy SimonsonDaniela LamattinaCristian A HumeresTapan BhattacharyyaPascal MertensCaroline ThunissenVictoria O'RourkeMagdalena PańczukJames A WhitworthOscar Daniel SalomonMichael A Miles
Published in: PLoS neglected tropical diseases (2021)
Seroprevalence confirmed rapid increase in CVL in Puerto Iguazú. The rK28 RDT test potentially has great value for improved point-of-care diagnosis. Given cost reduction and accessibility, commercial LAMP may be applicable to buffy coat. RDT biomarkers of CVL clinical status are required to combat spread of CVL and HVL. The presence of Viannia, perhaps as an agent of human mucocutaneous leishmaniasis (MCL), highlights the need for vigilance and surveillance.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • public health
  • loop mediated isothermal amplification
  • signaling pathway