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Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy.

Kathrin HeinrichLaura E FischerEnrico N De ToniDaniel MarkwardtDaniel RoesslerGeorg BeyerMichael GüntherSteffen OrmannsFrederick KlauschenWolfgang Gerhard KunzStefan FröhlingTilman BrummerVolker HeinemannChristoph Benedikt Westphalen
Published in: JCO precision oncology (2023)
In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI.
Keyphrases
  • case report
  • metastatic colorectal cancer
  • wild type
  • signaling pathway
  • late onset
  • oxidative stress
  • amyotrophic lateral sclerosis
  • cell proliferation