Tilman Brummer

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Topics

Acute Myeloid Leukemia

Tyrosine Kinase

Top Venues

Nature communications

JCO precision oncology

NPJ precision oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Adinarayana Marada, Corvin Walter, Tamara Suhm, Sahana Shankar, Arpita Nandy, Tilman Brummer, Ines Dhaouadi, Friederike-Nora Vögtle, Chris Meisinger
DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring. Nature communications 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Adinarayana Marada, Corvin Walter, Tamara Suhm, Sahana Shankar, Arpita Nandy, Tilman Brummer, Ines Dhaouadi, Friederike-Nora Vögtle, Chris Meisinger
DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring. Nature communications 15 (1) (2024)
Michael Huber, Tilman Brummer
Enzyme Is the Name-Adapter Is the Game. Cells 13 (15) (2024)
Julia C Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesus Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H Heiland, Roman Sankowski, Florian Scherer
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors. NPJ precision oncology 8 (1) (2024)
Julia C Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesus Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H Heiland, Roman Sankowski, Florian Scherer
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors. NPJ precision oncology 8 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Adinarayana Marada, Corvin Walter, Tamara Suhm, Sahana Shankar, Arpita Nandy, Tilman Brummer, Ines Dhaouadi, Friederike-Nora Vögtle, Chris Meisinger
DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring. Nature communications 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Michael Huber, Tilman Brummer
Enzyme Is the Name-Adapter Is the Game. Cells 13 (15) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Adinarayana Marada, Corvin Walter, Tamara Suhm, Sahana Shankar, Arpita Nandy, Tilman Brummer, Ines Dhaouadi, Friederike-Nora Vögtle, Chris Meisinger
DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring. Nature communications 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Julia C Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesus Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H Heiland, Roman Sankowski, Florian Scherer
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors. NPJ precision oncology 8 (1) (2024)
Dominik Schmidt, Cornelia Endres, Rouven Hoefflin, Geoffroy Andrieux, Melissa Zwick, Nikolaos Karantzelis, Hans F Staehle, Janaki Manoja Vinnakota, Sandra Duquesne, Miriam Mozaffari Jovein, Dietmar Pfeifer, Heiko Becker, Bruce R Blazar, Alexander Zähringer, Justus Duyster, Tilman Brummer, Melanie Börries, Julian Baumeister, Khalid Shoumariyeh, Juan Li, Anthony R Green, Florian H Heidel, Michael Mints, Heike Luise Pahl, Nils Bastian Leimkühler, Natalie Stickel, Marcelo Augusto Szymanski de Toledo, Steffen Koschmieder, Robert Zeiser
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment. Cancer research (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Daniel Christen, Manuel Lauinger, Melanie Brunner, Jörn Dengjel, Tilman Brummer
The mTOR pathway controls phosphorylation of BRAF at T401. Cell communication and signaling : CCS 22 (1) (2024)
Kathrin Heinrich, Laura E Fischer, Enrico N De Toni, Daniel Markwardt, Daniel Roessler, Georg Beyer, Michael Günther, Steffen Ormanns, Frederick Klauschen, Wolfgang Gerhard Kunz, Stefan Fröhling, Tilman Brummer, Volker Heinemann, Christoph Benedikt Westphalen
Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy. JCO precision oncology 7 (2023)
Marlene Langenbach, Sophie Giesler, Stefan Richtsfeld, Sara Costa-Pereira, Lukas Rindlisbacher, Tobias Wertheimer, Lukas M Braun, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Nadine M Woessner, Hans D Menssen, Sanaz Taromi, Justus Duyster, Melanie Börries, Tilman Brummer, Bruce R Blazar, Susana Minguet, Patrick Turko, Mitchell Paul Levesque, Burkhard Becher, Robert Zeiser
MDM2 inhibition enhances immune checkpoint inhibitor efficacy by increasing IL-15 and MHC class II production. Molecular cancer research : MCR (2023)
Manuel Lauinger, Daniel Christen, Rhena F U Klar, Carole Roubaty, Christoph E Heilig, Michael Stumpe, Jennifer J Knox, Nikolina Radulovich, Laura Tamblyn, Irene Y Xie, Peter Horak, Andrea Forschner, Michael Bitzer, Uwe A Wittel, Melanie Börries, Claudia R Ball, Christoph Heining, Hanno Glimm, Martina Fröhlich, Daniel Hübschmann, Steven Gallinger, Ralph Fritsch, Stefan Fröhling, Grainne M O'Kane, Joern Dengjel, Tilman Brummer
BRAF Δβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability. Science advances 9 (35) (2023)
Lino Rohrer, Corinna Spohr, Carina Beha, Ricarda Herr, Sandra Braun, Sebastian Halbach, Tilman Brummer
Analysis of RAS and drug induced homo- and heterodimerization of RAF and KSR1 proteins in living cells using split Nanoluc luciferase. Cell communication and signaling : CCS 21 (1) (2023)
Kathrin Heinrich, Laura E Fischer, Enrico N De Toni, Daniel Markwardt, Daniel Roessler, Georg Beyer, Michael Günther, Steffen Ormanns, Frederick Klauschen, Wolfgang Gerhard Kunz, Stefan Fröhling, Tilman Brummer, Volker Heinemann, Christoph Benedikt Westphalen
Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy. JCO precision oncology 7 (2023)
Romain Sigaud, Thomas Karl Albert, Caroline Hess, Thomas Hielscher, Nadine Winkler, Daniela Kocher, Carolin Walter, Daniel Münter, Florian Selt, Diren Usta, Jonas Ecker, Angela Brentrup, Martin Hasselblatt, Christian Thomas, Julian Varghese, David Capper, Ulrich W Thomale, Pablo Hernáiz Driever, Michèle Simon, Svea Horn, Nina Annika Herz, Arend Koch, Felix Sahm, Stefan Hamelmann, Augusto Faria Andrade, Nada Jabado, Martin Ulrich Schuhmann, Antoinette Y N Schouten-van Meeteren, Eelco Wieger Hoving, Tilman Brummer, Cornelis M van Tilburg, Stefan M Pfister, Olaf Witt, David T W Jones, Kornelius Kerl, Till Milde
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas. Nature communications 14 (1) (2023)
Kathrin Heinrich, Laura E Fischer, Enrico N De Toni, Daniel Markwardt, Daniel Roessler, Georg Beyer, Michael Günther, Steffen Ormanns, Frederick Klauschen, Wolfgang Gerhard Kunz, Stefan Fröhling, Tilman Brummer, Volker Heinemann, Christoph Benedikt Westphalen
Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy. JCO precision oncology 7 (2023)
Melanie Langhammer, Julia Schöpf, Timo Jaquet, Katharina Horn, Moritz Angel, Corinna Spohr, Daniel Christen, Franziska Maria Uhl, Tiago Maié, Henrike Jacobi, Thorsten B Feyerabend, Julia Huber, Marcus Panning, Cassian Sitaru, Ivan G Costa, Robert Zeiser, Konrad Aumann, Heiko Becker, Till Braunschweig, Steffen Koschmieder, Khalid Shoumariyeh, Michael Huber, Mirle Schemionek-Reinders, Tilman Brummer, Sebastian Halbach
Mast cell deficiency prevents BCR::ABL1 induced splenomegaly and cytokine elevation in a CML mouse model. Leukemia (2023)
Aladin Haimovici, Christoph Höfer, Mohamed Tarek Badr, Elham Bavafaye Haghighi, Tarek Amer, Melanie Boerries, Peter Bronsert, Ievgen Glavynskyi, Deborah Fanfone, Gabriel Ichim, Nico Thilmany, Arnim Weber, Tilman Brummer, Corinna Spohr, Rupert Öllinger, Klaus-Peter Janssen, Roland Rad, Georg Häcker
Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse. Cell death & disease 13 (4) (2022)
Corvin Walter, Adinarayana Marada, Tamara Suhm, Ralf Ernsberger, Vera Muders, Cansu Kücükköse, Pablo Sánchez-Martín, Zehan Hu, Abhishek Aich, Stefan Loroch, Fiorella Andrea Solari, Daniel Poveda-Huertes, Alexandra Schwierzok, Henrike Pommerening, Stanka Matic, Jan Brix, Albert Sickmann, Claudine Kraft, Joern Dengjel, Sven Dennerlein, Tilman Brummer, F-Nora Vögtle, Chris Meisinger
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery. Nature communications 12 (1) (2021)
Franziska Maria Uhl, Sophia Chen, David O'Sullivan, Joy Edwards-Hicks, Gesa Richter, Eileen Haring, Geoffroy Andrieux, Sebastian Halbach, Petya Apostolova, Jörg Büscher, Sandra Duquesne, Wolfgang Melchinger, Barbara Sauer, Khalid Shoumariyeh, Annette Schmitt-Graeff, Marina Kreutz, Michael Lübbert, Justus Duyster, Tilman Brummer, Melanie Börries, Tobias Madl, Bruce R Blazar, Olaf Gross, Erika L Pearce, Robert Zeiser
Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans. Science translational medicine 12 (567) (2021)
Corinna Spohr, Teresa Poggio, Geoffroy Andrieux, Katharina Schönberger, Nina Cabezas-Wallscheid, Melanie Börries, Sebastian Halbach, Anna L Illert, Tilman Brummer
Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo. Leukemia 36 (4) (2021)
Antonella Catalano, Mojca Adlesic, Thorsten Kaltenbacher, Rhena F U Klar, Joachim Albers, Philipp Seidel, Laura P Brandt, Tomas Hejhal, Philipp Busenhart, Niklas Röhner, Kyra Zodel, Kornelia Fritsch, Peter J Wild, Justus Duyster, Ralph Fritsch, Tilman Brummer, Ian J Frew
Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition. Cancers 13 (8) (2021)
Rouven Hoefflin, Adriana Lazarou, Maria Elena Hess, Meike Reiser, Julius Wehrle, Patrick Metzger, Anna Verena Frey, Heiko Becker, Konrad Aumann, Kai Berner, Martin Boeker, Nico Buettner, Christine Dierks, Jesus Duque-Afonso, Michel Eisenblaetter, Thalia Erbes, Ralph Fritsch, Isabell Xiang Ge, Anna-Lena Geißler, Markus Grabbert, Steffen Heeg, Dieter Henrik Heiland, Simone Hettmer, Gian Kayser, Alexander Keller, Anita Kleiber, Alexandra Kutilina, Leman Mehmed, Frank Meiss, Philipp Poxleitner, Justyna Rawluk, Juri Ruf, Henning Schäfer, Florian Scherer, Khalid Shoumariyeh, Andreas Tzschach, Christoph Peters, Tilman Brummer, Martin Werner, Justus Duyster, Silke Lassmann, Cornelius Miething, Melanie Börries, Anna L Illert, Nikolas von Bubnoff
Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis. Cancers 13 (5) (2021)
Lena Osswald, Shaima'a Hamarsheh, Franziska Maria Uhl, Geoffroy Andrieux, Claudius Klein, Christine Dierks, Sandra Duquesne, Lukas M Braun, Annette Schmitt-Graeff, Justus Duyster, Melanie Börries, Tilman Brummer, Robert Zeiser
Oncogenic KrasG12D Activation in the Nonhematopoietic Bone Marrow Microenvironment Causes Myelodysplastic Syndrome in Mice. Molecular cancer research : MCR 19 (9) (2021)
Diren Usta, Romain Sigaud, Juliane L Buhl, Florian Selt, Viktoria Marquardt, David Pauck, Jennifer Jansen, Stefan Pusch, Jonas Ecker, Thomas Hielscher, Johanna Vollmer, Alexander C Sommerkamp, Tobias Rubner, Darren R Hargrave, Cornelis M van Tilburg, Stefan M Pfister, David T W Jones, Marc Remke, Tilman Brummer, Olaf Witt, Till Milde
A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in BRAF-Driven Pediatric Low-Grade Glioma Cells. Molecular cancer therapeutics 19 (8) (2020)
Stephanie Ketterer, Julia Mitschke, Anett Ketscher, Manuel Schlimpert, Wilfried Reichardt, Natascha Baeuerle, Maria Elena Hess, Patrick Metzger, Melanie Börries, Christoph Peters, Bernd Kammerer, Tilman Brummer, Florian Steinberg, Thomas Reinheckel
Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling. Nature communications 11 (1) (2020)
Nadine Reischmann, Geoffroy Andrieux, Ricarda Herr, Thomas Reinheckel, Melanie Boerries, Tilman Brummer
BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation. Oncogene 39 (38) (2020)
Florian Weinberg, Ricarda Herr, Martina Fröhlich, Christoph Heining, Sandra Braun, Corinna Spohr, Mary Iconomou, Viola Hollek, Michael Röring, Peter Horak, Simon Kreutzfeldt, Gregor Warsow, Barbara Hutter, Sebastian Uhrig, Olaf Neumann, David Reuss, Dieter Henrik Heiland, Christof von Kalle, Wilko Weichert, Albrecht Stenzinger, Benedikt Brors, Hanno Glimm, Stefan Fröhling, Tilman Brummer
Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains. Oncogene 39 (4) (2019)
Martin Köhler, Sophia Ehrenfeld, Sebastian Halbach, Manuel Lauinger, Ulrike Burk, Nadine Reischmann, Shuofei Cheng, Corinna Spohr, Franziska Maria Uhl, Natalie Köhler, Kathrin Ringwald, Sandra Braun, Christoph Peters, Robert Zeiser, Thomas Reinheckel, Tilman Brummer
B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model. Oncogene 38 (8) (2019)
Alessandro Prestipino, Alica J Emhardt, Konrad Aumann, David O'Sullivan, Sivahari P Gorantla, Sandra Duquesne, Wolfgang Melchinger, Lukas M Braun, Slavica Vuckovic, Melanie Boerries, Hauke Busch, Sebastian Halbach, Sandra Pennisi, Teresa Poggio, Petya Apostolova, Pia Veratti, Michael Hettich, Gabriele Niedermann, Mark D Bartholomä, Khalid Shoumariyeh, Jonas Samuel Jutzi, Julius Wehrle, Christine Dierks, Heiko Becker, Annette Schmitt-Graeff, Marie Follo, Dietmar Pfeifer, Jan C Rohr, Sebastian Fuchs, Stephan Ehl, Frederike A Hartl, Susana Minguet, Christoph Cornelius Miething, Florian H Heidel, Nicolaus M Kröger, Ioanna Triviai, Tilman Brummer, Jürgen Finke, Anna L Illert, Eliana Ruggiero, Chiara Bonini, Justus Duyster, Heike Luise Pahl, Steven W Lane, Geoffrey R Hill, Bruce R Blazar, Nikolas von Bubnoff, Erika L Pearce, Robert Zeiser
Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Science translational medicine 10 (429) (2019)
Ricarda Herr, Sebastian Halbach, Miriam Heizmann, Hauke Busch, Melanie Börries, Tilman Brummer
BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines. Oncogene 37 (12) (2018)
Prisca Brauns-Schubert, Florian Schubert, Manuela Wissler, Martina Weiss, Lisa Schlicher, Simon Bessler, Mariam Safavi, Cornelius Miething, Christoph Borner, Tilman Brummer, Ulrich Maurer
CDK9-mediated phosphorylation controls the interaction of TIP60 with the transcriptional machinery. EMBO reports 19 (2) (2018)
Britta Diedrich, Kristoffer Tg Rigbolt, Michael Röring, Ricarda Herr, Stephanie Kaeser-Pebernard, Christine Gretzmeier, Robert F Murphy, Tilman Brummer, Joern Dengjel
Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition. The EMBO journal 36 (5) (2017)