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Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.

Riley M BoveEllis PatrickCristin McCabe AubinGyan SrivastavaJulie A SchneiderDavid A BennettPhilip L De JagerLori B Chibnik
Published in: PloS one (2018)
This study provides evidence from both a supervised and unsupervised analyses, that lifetime cumulative endogenous steroid exposures may play a role in maintenance of post-menopausal cellular balance, including in brain tissue.
Keyphrases
  • prefrontal cortex
  • machine learning
  • endothelial cells
  • dna methylation
  • gene expression
  • air pollution
  • induced pluripotent stem cells
  • multiple sclerosis
  • pluripotent stem cells