Exercise Inhibits Doxorubicin-Induced Cardiotoxicity via Regulating B Cells.

Jing WangShuqin LiuXinxiu MengXuan ZhaoTianhui WangZhiyong Lei Helge Immo Lehmann Guoping Li Pilar Alcaide Yihua Bei Junjie Xiao

Published in: Circulation research (2024)

Our results demonstrate that exercise training protects against Dox-induced cardiotoxicity by upregulating Fc gamma receptor IIB expression in B cells, which plays an important anti-inflammatory role and participates in the protective effect of exercise against Dox-induced cardiotoxicity.

Keyphrases

high glucose
diabetic rats
anti inflammatory
physical activity
high intensity
poor prognosis
drug induced
drug delivery
endothelial cells
skeletal muscle
resistance training
binding protein