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Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology.

Berke KaraahmetLinh H D LeMonique S MendesAnia Katarzyna MajewskaM Kerry O'Banion
Published in: Journal of neuroinflammation (2022)
Overall, we found that depleting and repopulating microglia causes overexpression of microglial Cxcl13 with disparate effects on Tau and amyloid pathologies.
Keyphrases
  • inflammatory response
  • neuropathic pain
  • cerebrospinal fluid
  • poor prognosis
  • lipopolysaccharide induced
  • lps induced
  • cell proliferation
  • spinal cord
  • spinal cord injury
  • transcription factor
  • protein kinase