Transplantation of insulin-producing cells derived from human MSCs to treat diabetes in a non-human primate model.

Zhu ZhoujunFeng BingzhengYang YuweiZhang YingyingXu ZhiranHe ChunhuaLeng JingTang HaiboLi WanliZhang TingLi FujunJi-Bing ChenGao Hongjun

Published in: Artificial organs (2023)

we present the novel discovery that IPCs derived from human umbilical cord MSCs exert a therapeutic effect in a non-human primate model of diabetes. This study provides a preliminary experimental basis for the use of autologous MSC-derived IPCs in the treatment of human diabetes.

Keyphrases

endothelial cells
type diabetes
mesenchymal stem cells
induced pluripotent stem cells
umbilical cord
cardiovascular disease
pluripotent stem cells
small molecule
high throughput
cell death
cell therapy
adipose tissue
cell proliferation
single cell