Efficacy of one-stage cartilage repair using allogeneic mesenchymal stromal cells and autologous chondron transplantation (IMPACT) compared to nonsurgical treatment for focal articular cartilage lesions of the knee: study protocol for a crossover randomized controlled trial.

J V KorpershoekL A VonkE C KesterL B CreemersT S de WindtM M A KipD B F SarisRoel Jh Custers

Published in: Trials (2020)

NL67161.000.18 [Registry ID: CCMO] 2018#003470#27 [EU-CTR; registered on 26 March 2019] NCT04236739 [ ClinicalTrials.gov ] [registered after start of inclusion; 22 January 2020].

Keyphrases

bone marrow
randomized controlled trial
stem cell transplantation
cell therapy
total knee arthroplasty
study protocol
open label
knee osteoarthritis
mesenchymal stem cells
clinical trial
low dose
stem cells
high dose
combination therapy
platelet rich plasma
replacement therapy
placebo controlled