Reduced Expression of Antimicrobial Protein Secretory Leukoprotease Inhibitor and Clusterin in Chronic Rhinosinusitis with Nasal Polyps.

Yanran Huang Ming Wang Yu Hong Xiangting Bu Ge Luan Yang WangYing LiHongfei Lou Chengshuo Wang Luo Zhang

Published in: Journal of immunology research (2021)

The expression of major antimicrobial proteins is significantly decreased in nasal tissue of CRSwNP. The expression of SLPI and CLU is correlated with the numbers of submucosal glands and regulated by inflammatory cytokines and glucocorticoids.

Keyphrases

chronic rhinosinusitis
poor prognosis
binding protein
staphylococcus aureus
small molecule