The association between vitamin D receptor polymorphisms and tissue-specific insulin resistance in human obesity.
Adriyan PramonoJ W E JockenM E AdriaensMads F HjorthArnie AstrupWim H M SarisEllen E BlaakPublished in: International journal of obesity (2005) (2021)
The VDR Fokl variant is associated with elevated circulating FFA and Adipo-IR at baseline. Nevertheless, minor to no effect of VDR SNPs on the transcriptional level in SAT, indicating that putative mechanisms of action remain to be determined. Finally, VDR SNPs did not affect dietary intervention outcome in the present cohort.