Identification of functional regulatory elements in the human genome using pooled CRISPR screens.

Published in: BMC genomics (2020)

This work diversifies the applications for pooled CRISPR screens and provides a framework for future functional studies focused on noncoding regulatory elements.

Keyphrases

genome wide
dna methylation
crispr cas
genome editing
endothelial cells
transcription factor
high throughput
induced pluripotent stem cells
single cell
bioinformatics analysis