Quercetin Stimulates Bone Marrow Mesenchymal Stem Cell Differentiation through an Estrogen Receptor-Mediated Pathway.

Xin-Gang PangYu CongNi-Rong BaoYong-Gang LiJian-Ning Zhao

Published in: BioMed research international (2018)

Our data demonstrated that quercetin promotes BMSC proliferation and osteogenic differentiation. Quercetin enhances BMP signaling pathway activation and upregulates the expression of downstream genes, such as OSX, RUNX2, and OPN, via the ER.

Keyphrases

estrogen receptor
mesenchymal stem cells
bone marrow
signaling pathway
umbilical cord
poor prognosis
pi k akt
cell therapy
genome wide
electronic health record
transcription factor
big data
stem cells
dna methylation
cell proliferation
breast cancer cells
artificial intelligence
long non coding rna