Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer.

Marta WagnerMaciej SobczyńskiMonika JasekKonrad PawełczykIrena PorębskaPiotr KuśnierczykAndrzej Wiśniewski

Published in: BMC cancer (2023)

Down-regulation of ERAP1 mRNA observed in NSCLC tissue may be related to tumor immune evasion strategy. The rs26653 polymorphism can be considered an expression quantitative trait locus (eQTL) associated with ERAP1 expression in normal lung tissue.

Keyphrases

poor prognosis
binding protein
small cell lung cancer
genome wide
high resolution
advanced non small cell lung cancer
dna methylation