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Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study.

Vanessa Y TanCaroline J BullKalina M BiernackaAlexander TeumerTom G RichardsonEleanor SandersonLaura J CorbinTom DuddingQibin QiRobert C KaplanJerome I RotterNele FriedrichUwe VölkerJulia MayerleClaire Marie PerksJeff M P HollyNicholas J Timpson
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2021)
Our findings should be considered in the development of prevention strategies for breast cancer, where interventions are known to modify circulating lipids and IGF-I.
Keyphrases
  • breast cancer risk
  • pi k akt
  • binding protein
  • physical activity
  • fatty acid
  • growth hormone
  • signaling pathway