Prediction of Effectiveness and Toxicities of Immune Checkpoint Inhibitors Using Real-World Patient Data.
Levente LippenszkyKathleen F MittendorfZoltán KissMichele L LeNoue-NewtonPablo Napan-MolinaProtiva RahmanCheng YeBalázs LacziEszter CsernaiNeha M JainMarilyn E HoltChristina N MaxwellMadeleine BallYufang MaMargaret B MitchellDouglas B JohnsonDavid S SmithBen Ho ParkChristine M MicheelDaniel FabbriJan WolberTravis J OstermanPublished in: JCO clinical cancer informatics (2024)
To our knowledge, this is the first ML solution that assesses individual ICI risk-benefit profiles based predominantly on routine structured EHR data. As such, use of our ML solution will not require additional data collection or documentation in the clinic.