Nimotuzumab and radiotherapy for treatment of newly diagnosed diffuse intrinsic pontine glioma (DIPG): a phase III clinical study.

Gudrun FleischhackM MassiminoM Warmuth-MetzE KhuhlaevaG JanssenN GrafS RutkowskiA BeilkenI SchmidV BiassoniS K GorelishevC KrammH ReinhardP G SchlegelR-D KortmannD ReuterF BachN E Iznaga-EscobarU Bode

Published in: Journal of neuro-oncology (2019)

Concomitant treatment with RT and nimotuzumab was feasible in an outpatient setting. The PFS and OS were comparable to results achieved with RT and intensive chemotherapy in hospitalized setting.

Keyphrases

phase iii
newly diagnosed
clinical trial
open label
early stage
locally advanced
radiation therapy
squamous cell carcinoma
randomized controlled trial
low grade
radiation induced
phase ii
study protocol