Empiric vs screening-based use of isoniazid for tuberculosis prophylaxis: Safety and effectiveness in lung transplant recipients in Saudi Arabia.

Ghazwa B KorayemDema A AlissaNorah I AlSuhaibaniGhaliah S AlSwailemMonifah A AlShammariImran YaqoobDoaa S AljasserReem Saad Almaghrabi

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2020)

The low rates of TB infection, INH-induced hepatotoxicity, and INH resistance in the EP group suggest that INH prophylaxis appears to prevent TB and can be safely used in all LT recipients. However, prospective studies using large sample sizes are required to confirm these findings.

Keyphrases

mycobacterium tuberculosis
drug induced
pulmonary tuberculosis
high glucose
randomized controlled trial
diabetic rats
systematic review
endothelial cells
urinary tract infection
oxidative stress
hiv aids
adverse drug