Placental Delta-Like 1 Gene DNA Methylation Levels Are Related to Mothers' Blood Glucose Concentration.
Bai-Hui ZhaoYing JiangHong ZhuFang-Fang XiYuan ChenYe-Tao XuFang LiuYa-Yun WangWen-Sheng HuWei-Guo LvQiong LuoPublished in: Journal of diabetes research (2019)
Our results demonstrated that altered expression of DLK1 was caused by the hypermethylation of DLK1 promoter region in the placenta, and intrauterine exposure to GDM has long-lasting effects on the epigenome of the offspring.