Development and Validation of a Combined Hypoxia and Immune Prognostic Classifier for Head and Neck Cancer.
Jill M BrooksAlbert N MenezesMaha IbrahimLucinda ArcherNeeraj LalChristopher J BagnallSandra Lucia Ventorin Von ZeidlerHelen R ValentineRachel J SpruceNikolaos BatisJennifer L BryantMargaret HartleyBaksho KaulGordon B RyanRiyue BaoArun KhattriSteven P LeeKalu U E OgburekeGary MiddletonDaniel A TennantAndrew D BeggsJonathan J DeeksCatharine M L WestJean-Baptiste CazierBenjamin E WillcoxTanguy Y SeiwertHisham MehannaPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
We developed and validated a hypoxia-immune prognostic transcriptional classifier, which may have clinical application to guide the use of hypoxia modification and targeted immunotherapies for the treatment of HNC.