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Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants.

Loes C A Rutten-JacobsSusanna C LarssonRainer MalikKristiina Rannikmäenull nullnull nullCathie L SudlowMartin DichgansHugh S MarkusMatthew Traylor
Published in: BMJ (Clinical research ed.) (2018)
In this cohort study, genetic and lifestyle factors were independently associated with incident stroke. These results emphasise the benefit of entire populations adhering to a healthy lifestyle, independent of genetic risk.
Keyphrases
  • cardiovascular disease
  • metabolic syndrome
  • genome wide
  • weight loss
  • physical activity
  • atrial fibrillation
  • copy number
  • cross sectional
  • brain injury
  • breast cancer risk