Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo quality.

Riddhi Kirit PandyaAmeya JijoAswathi CheredathShubhashree UppangalaSujith Raj SalianVani R LakshmiPratap KumarGuruprasad KalthurSanjay GuptaSatish Kumar Adiga
Published in: Andrology (2023)
Histone retention in spermatozoa can be one of the factors behind the development of idiopathic male infertility. Such spermatozoa may influence embryonic behaviour and thereby affect the success rate of assisted reproductive technology procedures. These results, although descriptive in nature, warrant further research to address the underlying mechanisms behind these clinically important observations.