High impact of macroaggregated albumin-based tumour dose on response and overall survival in hepatocellular carcinoma patients treated with 90 Y-loaded glass microsphere radioembolization.

Etienne GarinYan RollandMarc PrachtSamuel Le SourdSophie LaffontHabiba MesbahLaure-Anne HaumontLaurence LenoirTanguy RohouVanessa BrunJulien Edeline

Published in: Liver international : official journal of the International Association for the Study of the Liver (2016)

This study confirms the highly predictive value of MAA-based TD evaluation for response and OS. TD evaluation and PVT MAA targeting should be further evaluated in ongoing trials, whereas personalized dosimetry should be implemented in new trial designs.

Keyphrases

cancer therapy
drug delivery
study protocol
randomized controlled trial
phase iii
open label
wound healing