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Efficacy of Olanzapine-Triple Antiemetic Regimen in Patients with Gastrointestinal Tumor and High Risk of Chemotherapy-Induced Nausea and Vomiting Receiving Moderately Emetogenic Chemotherapy: A Retrospective Study.

Xuan WuJingxun WuGangling TongBoran ChengMinhua ChenShaokang YuLirui HeZhu LiShubin Wang
Published in: Cancer management and research (2020)
This retrospective study indicates that in gastrointestinal tumor patients with high-risk factors for CINV who were receiving MEC, olanzapine-containing triple antiemetic regimen exhibit better efficacy and QoL as compared to non-olanzapine dual regimen. Further randomized studies are required to confirm these results.
Keyphrases
  • chemotherapy induced
  • double blind
  • randomized controlled trial
  • clinical trial
  • placebo controlled
  • study protocol