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No increased suggestibility to placebo in functional neurological disorder.

Anne-Catherine M L HuysBrianna BeckPatrick HaggardKailash P BhatiaMark John Edwards
Published in: European journal of neurology (2021)
Patients with FND did not have stronger placebo responses than healthy controls. The notion of generally increased suggestibility or increased suggestibility to placebo in FND seems mistaken. Instead, occasional dramatic placebo responses may occur because functional symptoms are inherently more changeable than those due to organic disease.
Keyphrases
  • double blind
  • phase iii
  • placebo controlled
  • randomized controlled trial
  • open label
  • blood brain barrier
  • cerebral ischemia