Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer.

Kazuto Suda Atsushi Okabe Junichi Matsuo Linda Shyue Huey Chuang Ying Li Nawaphat Jangphattananont Naing Naing Mon Khine Nyein Myint Akihiro Yamamura Jimmy Bok-Yan So Dominic Chih-Cheng Voon Henry Yang Khay-Guan Yeoh Atsushi Kaneda Yoshiaki Ito

Published in: Cancer research communications (2024)

Subversion of RUNX3 developmental gene targets to metastasis program indicates the oncogenic nature of inappropriate RUNX3 regulation in gastric cancer.

Keyphrases

transcription factor
genome wide identification
genome wide
quality improvement
copy number
poor prognosis
signaling pathway
gene expression
genome wide analysis