Effectiveness of first and second-line empirical treatment in Italy: Results of the European registry on Helicobacter pylori management.
Luigi GattaOlga P NyssenGiulia FioriniIlaria Maria SaracinoMatteo PavoniMarco RomanoAntonietta Gerarda GravinaLucia GranataRinaldo PellicanoAntonio GasbarriniAlfredo Di LeoGiuseppe LosurdoFrancesco FranceschiGerardo NardoneAlba RoccoGiovanni Mario PesFabio FarinatiMatteo GhisaMassimo BelliniJohn HoltonIgnasi PuigDino VairaClaudio BorghiFrancis MégraudColm O'MorainFrancisco Javier García-AlonsoPublished in: United European gastroenterology journal (2022)
Only quadruple therapies lasting at least 10 days achieved over 90% eradication rates among the empirical first- and second-line regimens. It remains unclear whether high-dose PPI twice daily can improve the efficacy of quadruple treatment.