Network Meta-Analysis of Drug Therapies for Lowering Uric Acid and Mortality Risk in Patients with Heart Failure.

Satoru KodamaKazuya FujiharaChika HorikawaMayuko YamadaTakaaki SatoYuta YaguchiMasahiko YamamotoMasaru KitazawaYasuhiro MatsubayashiTakaho YamadaKenichi WatanabeHirohito Sone

Published in: Cardiovascular drugs and therapy (2020)

Results suggested that allopurinol therapy was not associated with a significantly improved prognosis in terms of mortality but could potentially counteract the adverse effects associated with longstanding hyperuricemia in HF patients.

Keyphrases

uric acid
systematic review
metabolic syndrome
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
cardiovascular events
prognostic factors
meta analyses
randomized controlled trial
risk factors
patient reported
case control