Human Umbilical Cord-Derived Mesenchymal Stem Cells Alleviate Acute Lung Injury Caused by Severe Burn via Secreting TSG-6 and Inhibiting Inflammatory Response.
Xiaohong HuLingying LiuYu WangChuanshu HuangZhongyuan LiYanan LiuJiake ChaiPublished in: Stem cells international (2022)
The intratracheal implantation of hUC-MSCs has been an effective treatment for severe burn-induced ALI via promoting TSG-6 secretion and inhibiting inflammatory reaction in lung tissue.
Keyphrases
- umbilical cord
- mesenchymal stem cells
- inflammatory response
- lipopolysaccharide induced
- lps induced
- endothelial cells
- signaling pathway
- high glucose
- drug induced
- early onset
- wound healing
- oxidative stress
- diabetic rats
- bone marrow
- induced pluripotent stem cells
- toll like receptor
- pluripotent stem cells
- replacement therapy
- smoking cessation
- electron transfer