Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?-observations from the UK JSLE Cohort Study.

Eve M D SmithSajida RasulCoziana CiurtinEslam Al-AbadiKate ArmonKathryn BaileyMary BrennanJanet Gardner-MedwinKirsty HaslamDaniel P HawleySteven LaneAlice LeahyValentina LeoneGulshan MalikDevesh MewarRobert MootsClarissa PilkingtonAthimalaipet V RamananSatyapal RangarajAnnie RatcliffePhil RileyEthan SenArani SridharNick WilkinsonMichael W BeresfordLiza J McCannChristian M Hedrich

Published in: Rheumatology (Oxford, England) (2021)

In CYP, the ACR/EULAR-2019 criteria are not superior to those of the SLICC-2012 or ACR-1997 criteria. If classification criteria are designed to include CYP and adult populations, paediatric rheumatologists should be included in the consensus and evaluation process, as seemingly minor changes can significantly affect outcomes.

Keyphrases

machine learning
deep learning
systemic lupus erythematosus
emergency department
cross sectional
clinical practice
weight loss
genetic diversity