Dysregulation of solute carrier transporters in malaria-infected pregnant mice.
Najwa NajjarEliza R McCollAndrea WeckmanKevin C KainMicheline Piquette-MillerPublished in: Parasite immunology (2019)
Malaria in pregnancy significantly alters the expression of SLC transporters in maternal and foetal tissues as well as the placenta, regardless of L-arginine supplementation. Further studies to investigate methods of reducing oxidative stress in MiP are warranted.
Keyphrases
- plasmodium falciparum
- oxidative stress
- pregnancy outcomes
- poor prognosis
- pregnant women
- nitric oxide
- preterm birth
- gene expression
- birth weight
- gestational age
- dna damage
- high fat diet induced
- ischemia reperfusion injury
- binding protein
- induced apoptosis
- diabetic rats
- body mass index
- long non coding rna
- skeletal muscle
- wild type
- physical activity
- insulin resistance
- signaling pathway
- heat shock