The treatment of advanced melanoma: a review of systemic and local therapies in combination with immune checkpoint inhibitors in phase 1 and 2 clinical trials.

Danielle K DePalo Ahmad A Tarhini Jonathan S Zager

Published in: Expert opinion on investigational drugs (2022)

Drug combinations discussed here appear to be promising therapeutic regimens for advanced melanoma. Improved understanding of the mechanisms of primary, adaptive, and acquired resistance to immune checkpoint inhibitors may guide the development of future combination regimens.

Keyphrases

clinical trial
skin cancer
randomized controlled trial
emergency department
drug induced
adverse drug
phase ii