Discovery of extracellular vesicle-delivered miR-185-5p in the plasma of patients as an indicator for advanced adenoma and colorectal cancer.
Yun-Jie ShiYu-Xiang FangTong-Guan TianWei-Ping ChenQiang SunFang-Qi GuoPi-Qing GongChun-Mei LiHao WangZhi-Qian HuXin-Xing LiPublished in: Journal of translational medicine (2023)
EV-delivered miR-185-5p in the plasma of patients is a promising diagnostic biomarker for colorectal AA and CRC. Trial registration The study protocol was approved by the Ethics Committee of Changzheng Hospital, Naval Medical University, China (Ethics No. 2022SL005, Registration No. of China Clinical Trial Registration Center: ChiCTR220061592).
Keyphrases
- clinical trial
- study protocol
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- healthcare
- public health
- prognostic factors
- small molecule
- emergency department
- phase ii
- machine learning
- patient reported outcomes
- phase iii
- high throughput
- open label
- deep learning
- patient reported
- electronic health record
- global health
- placebo controlled