TREM-1 and TREM-2 Expression on Blood Monocytes Could Help Predict Survival in High-Grade Glioma Patients.

K KluckovaJ KozakK SzaboovaB RychlyM SvajdlerMagda SuchankovaE TibenskaB FilovaJ StenoV MatejcikM HomolovaMaria Bucova

Published in: Mediators of inflammation (2020)

We showed that the TREM-1/TREM-2 ratio (expression on the surface of blood monocytes) could help predict prognosis in patients with gliomas, especially in high-grade gliomas, and that systemic inflammation has an impact on the patient's overall survival. This is the first study that showed that TREM expression on monocytes in peripheral blood could help predict prognosis in patients with gliomas.

Keyphrases

high grade
peripheral blood
low grade
poor prognosis
end stage renal disease
dendritic cells
chronic kidney disease
binding protein
long non coding rna
free survival
case report
peritoneal dialysis
immune response
patient reported outcomes