Short- and long-term outcomes of a disruption and disconnection of the pancreatic duct in necrotizing pancreatitis: a multicenter cohort study in 896 patients : Disrupted pancreatic duct in acute pancreatitis.
Hester C TimmerhuisSven M van DijkRobbert A HollemansChristina J Sperna WeilandDevica S UmansLotte BoxhoornNora H HallenslebenRogier van der SluijsLieke BrouwerPeter van DuijvendijkLiesbeth KagerSjoerd KuikenJan-Werner PoleyRogier de RidderTessa RömkensRutger QuispelMatthijs P SchwartzAdriaan C I T L TanNiels G VennemanFrank P VleggaarRoy L J van WanrooijBen J WittemanErwin van GeenenI Quintus MolenaarMarco J BrunoJeanin E van HooftMarc G BesselinkRogier P VoermansThomas L BollenRobert C VerdonkHjalmar C van Santvoortnull nullPublished in: The American journal of gastroenterology (2022)
At least one of every four patients with necrotizing pancreatitis suffer from DPD which is associated with detrimental, short and long-term interventions and complications. Central and subtotal pancreatic necrosis and high levels of serum CRP in the first 48 hours are independent predictors for DPD.