Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis.
Marianne EngströmKaja ErikssonLinkiat LeeMonika HermanssonAnders JohanssonAnthony P NicholasNatalija GerasimcikKarin LundbergLars KlareskogAnca Irinel CatrinaTülay Yucel-LindbergPublished in: Journal of translational medicine (2018)
Chronic gingival inflammation is associated with increased local citrullination and PAD2 and PAD4 expression in periodontitis. The increased citrullination and PAD2 and PAD4 expression in periodontitis were, however, independent of the presence of periodontal pathogen P. gingivalis and A. actinomycetemcomitans leukotoxin.