Improvement by Medication Less than Expected in Parkinson's Disease: Blinded Evaluation of Levodopa Response.
Mette Niemann JohansenAnna HandbergMohamed El HaddouchiJosefine GrundtvigSteen Rusborg JensenLisette SalvesenAnnemette LøkkegaardPublished in: Parkinson's disease (2024)
We showed an acute effect of levodopa using LDCT that was around 30% improvement. While it lends support to the use of this limit in the MDS diagnostic criteria, an acute effect of less than 30% should be considered acceptable in some patients. Our study highlights a discrepancy in the objective measure of medicine effect on motor symptoms and the patient's subjective evaluation.
Keyphrases
- liver failure
- end stage renal disease
- respiratory failure
- parkinson disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- deep brain stimulation
- drug induced
- prognostic factors
- peritoneal dialysis
- case report
- randomized controlled trial
- study protocol
- physical activity
- electronic health record
- acute respiratory distress syndrome
- depressive symptoms
- mechanical ventilation