ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban.
An-Jing RenChun-Chun WeiYa-Jin LiuMengna LiuPing WangJuan FanKai WangSha ZhangZhenbang QinQiu-Xiao RenYanjun ZhengYu-Xia ChenZhifang XieLing GaoYi ZhuYouyi ZhangHuang-Tian YangWeiping J ZhangPublished in: Circulation research (2024)
These data point to ZBTB20 act as a fine-tuning modulator of PLN expression and SERCA2a activity, thereby offering new perspective on the regulation of basal contractility in the mammalian heart.