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ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban.

An-Jing RenChun-Chun WeiYa-Jin LiuMengna LiuPing WangJuan FanKai WangSha ZhangZhenbang QinQiu-Xiao RenYanjun ZhengYu-Xia ChenZhifang XieLing GaoYi ZhuYouyi ZhangHuang-Tian YangWeiping J Zhang
Published in: Circulation research (2024)
These data point to ZBTB20 act as a fine-tuning modulator of PLN expression and SERCA2a activity, thereby offering new perspective on the regulation of basal contractility in the mammalian heart.
Keyphrases
  • poor prognosis
  • smooth muscle
  • heart failure
  • left ventricular
  • air pollution
  • electronic health record
  • big data
  • binding protein