Effects of sitagliptin on peritoneal membrane: The potential role of mesothelial cell tight junction proteins.

Chor Ho JoSua KimTae Kyung HaDuk-Hee KangGheun-Ho Kim

Published in: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis (2023)

The expression of TJ proteins including claudin-1 and claudin-15 was associated with transport function both in HPMCs and in a rat model of PD. Sitagliptin prevents peritoneal fibrosis in PD and can potentially restore peritoneal mesothelial cell TJ proteins.

Keyphrases

single cell
cell therapy
poor prognosis
stem cells
endothelial cells
high glucose
human health