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Quantification of lipid bodies in monocytes from patients with periodontitis.

Priscilla F NaiffSelma A S KuckelhausDanilo CorazzaLuciana M LeiteShirley CoutoMariangela S deOliveiraLuander M SantiagoLarissa F SilvaLaudimar A OliveiraDaniela C GrisiValeria M A CarneiroMaria do C M Guimarães
Published in: Clinical and experimental dental research (2020)
The data suggest that periodontitis may contribute to a higher production of lipid bodies. It was also hypothesized that a major production of lipid bodies by monocytes in severe periodontitis, compared to orally healthy subjects, could interfere with the innate immune response or represents a higher reservoir of cholesterol esters within macrophages and a major risk to systemic implications, such as atherosclerosis.
Keyphrases
  • immune response
  • dendritic cells
  • fatty acid
  • cardiovascular disease
  • peripheral blood
  • toll like receptor
  • electronic health record
  • big data
  • artificial intelligence
  • water quality