Comparison of Epidermal Gene Expression Profiles in Mice Aged 1 to 20 Months.

Xiaohua WangSi WenLi YeDan LiuMao-Qiang ManBin Yang

Published in: Clinical, cosmetic and investigational dermatology (2022)

These results indicate that the epidermis of aged mice displays an upregulation of genes associated with inflammatory signaling pathways, and downregulation of genes related to metabolic signaling pathways.

Keyphrases

signaling pathway
gene expression
high fat diet induced
pi k akt
cell proliferation
dna methylation
epithelial mesenchymal transition
induced apoptosis
genome wide
poor prognosis
long non coding rna
wild type
skeletal muscle
wound healing
clinical evaluation