Expression and Significance of Inflammatory Factors in Idiopathic Spinal Epidural Lipomatosis (Grade III).
Mingkun YangHang ZhangMinyi LiuXindong JiaTao DuDengpu WuPublished in: Neuro endocrinology letters (2024)
iSEL demonstrated elevated inflammatory cells and imbalance towards proinflammatory cytokines in adipocytes of epidural adipose tissue that may be associated with the pathogenesis of symptomatic iSEL. These data suggest that inflammatory response could be one of the mechanisms of iSEL. However, further multicenter epidemiological investigations and rigorous basic and clinical research are warranted to elucidate the specific etiology of iSEL.
Keyphrases
- adipose tissue
- spinal cord
- inflammatory response
- induced apoptosis
- oxidative stress
- poor prognosis
- insulin resistance
- high fat diet
- electronic health record
- lipopolysaccharide induced
- spinal cord injury
- clinical trial
- binding protein
- big data
- immune response
- cell proliferation
- deep learning
- data analysis
- artificial intelligence